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Mesenchymal regenerative medicine therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy – a review

Osteoarthritis, Research StudiesBy Regenerative Medicine Therapy Clinic January 28, 2019

Osteoarthritis is a leading cause of pain and disability across the world. With an aging population its prevalence is likely to further increase. Current accepted medical treatment strategies are aimed at symptom control rather than disease modification. Surgical options including joint replacement are not without possible significant complications. A growing interest in the area of regenerative medicine, led by an improved understanding of the role of mesenchymal regenerative medicines in tissue homeostasis and repair, has seen recent focused efforts to explore the potential of regenerative medicine therapies in the active management of symptomatic osteoarthritis.
https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-016-1085-9
Julien Freitag, Dan Bates, Richard Boyd, Kiran Shah, Adele Barnard, Leesa Huguenin and Abi Tenen

Prolotherapy and Low Level Laser Therapy: A Synergistic Approach to Pain Management in Chronic Osteoarthritis.

Research StudiesBy Regenerative Medicine Therapy Clinic January 28, 2019

Regenerative injection therapy and low level laser therapy are alternative remedies known for their success in the treatment and symptomatic management of chronic musculoskeletal conditions. In response to the growing demand for alternative therapies in the face of the opioid epidemic, the authors conduct a literature review to investigate the potential for prolotherapy and LLLT to be used adjunctively to manage chronic osteoarthritis (OA). OA is a degenerative chronic musculoskeletal condition on the rise in North America, and is frequently treated with opioid medications. The regenerative action of prolotherapy and pain-modulating effects of LLLT may make these two therapies well-suited to synergistically provide improved outcomes for osteoarthritis patients without the side effects associated with opioid use. A narrative descriptive review through multiple medical databases (Google Scholar, PubMed, and MedLine) is conducted, restricted by the use of medical subject headings. 71 articles were selected for reading in full, and 40 articles were selected for use in the study after reading in full.
https://www.ncbi.nlm.nih.gov/pubmed/29696113
Tieppo Francio V, Dima RS, Towery C, Davani S