Accumulating evidence indicates that every tissue contains regenerative medicines. Our understanding of the biology of regenerative medicines reveals that these cell populations have a critical role in the homeostasis and repair of tissues. Besides the local regenerative medicine niches, additional compartments in the body such as the bone marrow may serve as reservoirs for regenerative medicine populations. On more extensive tissue damage, and guided by local repair responses, “reparative” cell populations are mobilized from more distant regenerative medicine reservoirs and migrate to the site of injury, thereby contributing in many aspects of local tissue repair.
Frank P. Luyten